psdht protein (Legionella feeleii) - STRING interaction network

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Score

psdht

Phenylserine dehydratase. (301 aa)

Predicted Functional Partners:

budB

0.927

trpB

0.883

tdcG

0.869

glyA

0.867

ltaE

0.865

metB

0.864

tdh

0.851

trpA

0.851

pssA

0.842

pdhB_2

0.841

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
budB	metB	Lfee_2383	Lfee_0190	Acetolactate synthase; Belongs to the TPP enzyme family.	Cystathionine beta-lyase.	0.465
budB	pdhB_2	Lfee_2383	Lfee_1854	Acetolactate synthase; Belongs to the TPP enzyme family.	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	0.829
budB	psdht	Lfee_2383	Lfee_1208	Acetolactate synthase; Belongs to the TPP enzyme family.	Phenylserine dehydratase.	0.927
glyA	ltaE	Lfee_0067	Lfee_0567	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Low specificity L-threonine aldolase.	0.904
glyA	psdht	Lfee_0067	Lfee_1208	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phenylserine dehydratase.	0.867
glyA	pssA	Lfee_0067	Lfee_1191	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	CDP-diacylglycerol-serine O-phosphatidyltransferase (phosphatidylserine synthase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.843
glyA	tdcG	Lfee_0067	Lfee_1094	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.936
glyA	trpA	Lfee_0067	Lfee_3197	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.865
glyA	trpB	Lfee_0067	Lfee_3198	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.865
ltaE	glyA	Lfee_0567	Lfee_0067	Low specificity L-threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.904
ltaE	psdht	Lfee_0567	Lfee_1208	Low specificity L-threonine aldolase.	Phenylserine dehydratase.	0.865
ltaE	tdh	Lfee_0567	Lfee_0086	Low specificity L-threonine aldolase.	Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.	0.851
metB	budB	Lfee_0190	Lfee_2383	Cystathionine beta-lyase.	Acetolactate synthase; Belongs to the TPP enzyme family.	0.465
metB	pdhB_2	Lfee_0190	Lfee_1854	Cystathionine beta-lyase.	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	0.846
metB	psdht	Lfee_0190	Lfee_1208	Cystathionine beta-lyase.	Phenylserine dehydratase.	0.864
metB	tdcG	Lfee_0190	Lfee_1094	Cystathionine beta-lyase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.862
pdhB_2	budB	Lfee_1854	Lfee_2383	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	Acetolactate synthase; Belongs to the TPP enzyme family.	0.829
pdhB_2	metB	Lfee_1854	Lfee_0190	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	Cystathionine beta-lyase.	0.846
pdhB_2	psdht	Lfee_1854	Lfee_1208	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	Phenylserine dehydratase.	0.841
pdhB_2	tdh	Lfee_1854	Lfee_0086	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.	0.811