STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manCMannose-6-phosphate isomerase. (121 aa)    
Predicted Functional Partners:
Lfee_1057
Glutamate synthetase.
  
  0.603
metG
Methionyl tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.572
ugd
UDP-glucose 6-dehydrogenase.
  
 
 0.521
gmd_1
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.513
galU
Glucose-1-phosphate uridylyltransferase.
    
 0.492
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.480
Lfee_1222
Hypothetical protein.
       0.462
lysU
Lysine tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.458
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.451
iolCB
IolC/IolB transferase kinase protein; Belongs to the carbohydrate kinase PfkB family.
    
 0.443
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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