STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (342 aa)    
Predicted Functional Partners:
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
   
 0.954
Lfee_2668
Mevalonate diphosphate decarboxylase.
 
  
 0.927
Lfee_1275
Hypothetical protein.
    
 0.861
Lfee_2669
Putative mevalonate kinase.
 
  
 0.850
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.794
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.765
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
     
 0.667
pta
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.630
Lfee_2176
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.629
ispB
Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family.
  
 
 0.583
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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