Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ycgEHTH-type transcriptional repressor YcgE. (302 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.819
sahH
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.807
Lfee_1379
Hypothetical protein.
       0.790
lysAC_1
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.775
metG
Methionyl tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
  0.772
ycdT
Sensor histidine kinase.
   
 0.765
Lfee_0399
Regulatory protein (GGDEF domain).
   
 0.765
Lfee_1377
Fatty acid desaturase.
       0.752
tycC_2
Peptide synthetase, non-ribosomal.
   
 0.735
cyaA_1
Fused adenylate cyclase/two component hybrid sensor/regulator.
   
 0.733
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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