STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sfcA_1Malate dehydrogenase. (571 aa)    
Predicted Functional Partners:
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.814
cfiA_1
Oxaloacetate decarboxylase subunit alpha.
    
 0.793
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.792
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.708
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.685
budB
Acetolactate synthase; Belongs to the TPP enzyme family.
 
 
 0.683
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.658
pta
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
 
 0.601
tal
Transaldolase.
   
  
 0.593
odpB
Pyruvate dehydrogenase E1 subunit beta.
   
 
 0.586
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.