Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
per1Beta-lactamase. (351 aa)    
Predicted Functional Partners:
chiA1
Chitinase A1 precursor.
  
     0.620
chiD
Chitinase.
  
     0.583
carB_2
Carbamoyl-phosphate synthase large chain.
  
     0.479
Lfee_1791
Hypothetical protein.
  
     0.471
Lfee_1300
Two component response regulator.
  
     0.457
Lfee_0032
Phosphotransferase enzyme family protein.
  
     0.456
Lfee_0102
Hypothetical protein.
  
     0.450
Lfee_0228
Putative N-hydroxyarylamine O-acetyltransferase.
  
     0.446
Lfee_1592
Protein kinase domain protein.
       0.440
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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