Lfee_1622 protein (Legionella feeleii) - STRING interaction network

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Score

Lfee_1622

Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family. (190 aa)

Predicted Functional Partners:

clpA

0.716

clpB

0.716

htpG

0.538

Lfee_1621

0.529

dnaK

0.528

grpE

0.409

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_1621	Lfee_1622	Lfee_1621	Lfee_1622	Hypothetical protein.	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	0.529
Lfee_1622	Lfee_1621	Lfee_1622	Lfee_1621	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	Hypothetical protein.	0.529
Lfee_1622	clpA	Lfee_1622	Lfee_2875	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	0.716
Lfee_1622	clpB	Lfee_1622	Lfee_3021	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	Endopeptidase Clp ATP-binding subunit B; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.716
Lfee_1622	dnaK	Lfee_1622	Lfee_2138	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.528
Lfee_1622	grpE	Lfee_1622	Lfee_2139	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.409
Lfee_1622	htpG	Lfee_1622	Lfee_0531	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.	0.538
clpA	Lfee_1622	Lfee_2875	Lfee_1622	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	0.716
clpA	dnaK	Lfee_2875	Lfee_2138	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.980
clpA	grpE	Lfee_2875	Lfee_2139	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.851
clpA	htpG	Lfee_2875	Lfee_0531	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.	0.712
clpB	Lfee_1622	Lfee_3021	Lfee_1622	Endopeptidase Clp ATP-binding subunit B; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	0.716
clpB	dnaK	Lfee_3021	Lfee_2138	Endopeptidase Clp ATP-binding subunit B; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.980
clpB	grpE	Lfee_3021	Lfee_2139	Endopeptidase Clp ATP-binding subunit B; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.851
clpB	htpG	Lfee_3021	Lfee_0531	Endopeptidase Clp ATP-binding subunit B; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.	0.712
dnaK	Lfee_1622	Lfee_2138	Lfee_1622	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat shock hsp20; Belongs to the small heat shock protein (HSP20) family.	0.528
dnaK	clpA	Lfee_2138	Lfee_2875	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	0.980
dnaK	clpB	Lfee_2138	Lfee_3021	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Endopeptidase Clp ATP-binding subunit B; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.980
dnaK	grpE	Lfee_2138	Lfee_2139	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.999
dnaK	htpG	Lfee_2138	Lfee_0531	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.	0.999