Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yicOXanthine/uracil permease. (462 aa)    
Predicted Functional Partners:
Lfee_0057
SMP-30/Gluconolaconase/LRE-like region.
     
 0.786
Lfee_1715
Hypothetical protein.
       0.748
Lfee_1714
Hypothetical protein.
       0.667
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.625
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.504
purD
Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
  
  
 0.491
vipF
Hypothetical protein; N-terminal GNAT family acetyltransferase.
       0.489
iolCB
IolC/IolB transferase kinase protein; Belongs to the carbohydrate kinase PfkB family.
     
 0.480
pdxB
Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
     
  0.461
hprA
2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.446
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: medium (46%) [HD]