Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gorGlutathione reductase. (449 aa)    
Predicted Functional Partners:
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 0.989
btuE
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.935
odpB
Pyruvate dehydrogenase E1 subunit beta.
 
 0.921
sucB
Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.919
aceF
Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.914
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
     
 0.911
odp
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.903
ggt
Gamma-glutamyltranspeptidase.
     
 0.889
sucA
2-oxoglutarate dehydrogenase E1 component.
  
 0.887
merA1
Mercuric reductase.
    
 0.884
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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