Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Lfee_1964Hemolysin D. (314 aa)    
Predicted Functional Partners:
Lfee_1966
ABC transporter permease.
 
  
 0.979
ybhF
Fused transporter subunits of ABC superfamily: ATP-binding component.
  
 0.976
yrdA
Transferase.
       0.647
gor
Glutathione reductase.
       0.647
tolC_2
Outer membrane protein TolC.
  
 0.609
Lfee_1990
ABC transporter permease.
 
  
 0.582
mdtP_2
Outer membrane efflux protein.
 
 
 0.530
tolC_1
Outer membrane efflux protein.
  
  0.529
ttgC
Outer membrane efflux protein.
 
 
 0.520
acrA
Acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
     0.481
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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