Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolSAldo/keto reductase. (301 aa)    
Predicted Functional Partners:
ytbE
D-xylose reductase III.
 
 0.819
Lfee_2004
EamA-like transporter family protein.
   
   0.779
Lfee_2006
Carbon starvation induced protein.
     
 0.773
Lfee_2005
Hypothetical protein.
       0.768
hdaH
Histone deacetylase-like amidohydrolase.
   
  0.762
ycjS
Oxidoreductase.
 
 
 0.593
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
     
 0.573
ugd
UDP-glucose 6-dehydrogenase.
   
 
  0.554
iolCB
IolC/IolB transferase kinase protein; Belongs to the carbohydrate kinase PfkB family.
    
 0.528
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.527
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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