node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lfee_2003 | cysK | Lfee_2003 | Lfee_1728 | Aspartate aminotransferase. | Cystathionine beta synthase. | 0.598 |
Lfee_2003 | glyA | Lfee_2003 | Lfee_0067 | Aspartate aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.487 |
Lfee_2003 | pepA | Lfee_2003 | Lfee_2087 | Aspartate aminotransferase. | Leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.582 |
Lfee_2003 | pepA-2 | Lfee_2003 | Lfee_2085 | Aspartate aminotransferase. | Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.582 |
Lfee_2003 | pepN | Lfee_2003 | Lfee_1876 | Aspartate aminotransferase. | Aminopeptidase. | 0.542 |
cysK | Lfee_2003 | Lfee_1728 | Lfee_2003 | Cystathionine beta synthase. | Aspartate aminotransferase. | 0.598 |
cysK | ggt | Lfee_1728 | Lfee_0601 | Cystathionine beta synthase. | Gamma-glutamyltranspeptidase. | 0.602 |
cysK | glyA | Lfee_1728 | Lfee_0067 | Cystathionine beta synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.730 |
cysK | pepA | Lfee_1728 | Lfee_2087 | Cystathionine beta synthase. | Leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.600 |
cysK | pepA-2 | Lfee_1728 | Lfee_2085 | Cystathionine beta synthase. | Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.600 |
cysK | pepN | Lfee_1728 | Lfee_1876 | Cystathionine beta synthase. | Aminopeptidase. | 0.613 |
ggt | cysK | Lfee_0601 | Lfee_1728 | Gamma-glutamyltranspeptidase. | Cystathionine beta synthase. | 0.602 |
ggt | gshB | Lfee_0601 | Lfee_0792 | Gamma-glutamyltranspeptidase. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.622 |
ggt | pepA | Lfee_0601 | Lfee_2087 | Gamma-glutamyltranspeptidase. | Leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.598 |
ggt | pepA-2 | Lfee_0601 | Lfee_2085 | Gamma-glutamyltranspeptidase. | Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.598 |
ggt | pepN | Lfee_0601 | Lfee_1876 | Gamma-glutamyltranspeptidase. | Aminopeptidase. | 0.562 |
glyA | Lfee_2003 | Lfee_0067 | Lfee_2003 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate aminotransferase. | 0.487 |
glyA | cysK | Lfee_0067 | Lfee_1728 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cystathionine beta synthase. | 0.730 |
glyA | gmk | Lfee_0067 | Lfee_2276 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.597 |
glyA | pepA | Lfee_0067 | Lfee_2087 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.566 |