Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Lfee_2225Hypothetical protein. (347 aa)    
Predicted Functional Partners:
efp
Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
  
 0.824
Lfee_2226
Hypothetical protein.
       0.801
hlyB_1
ABC transporter.
       0.652
cvaA
Hemolysin D.
       0.652
Lfee_2227
Hypothetical protein.
       0.650
Lfee_2224
Hypothetical protein.
       0.601
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
 
  0.569
Lfee_2223
Hypothetical protein.
       0.527
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
   
 
  0.518
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
   0.423
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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