Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spkB_3Protein IcmE (DotG). (1090 aa)    
Predicted Functional Partners:
Lfee_2297
IcmK protein.
 
 
 
 0.993
Lfee_2291
Protein IcmB (DotO).
 
 0.989
dotC
Defect in organelle trafficking lipoprotein DotC.
  
 
 
 0.986
Lfee_2295
Protein IcmG (DotF).
   
 
 0.982
lphA
LphA (DotK).
 
 
 
 0.973
Lfee_2298
Protein IcmL (DotI).
 
   
 0.970
dotA
Defect in organelle trafficking protein DotA.
  
 
   0.968
virB4
Type IV secretory protein VirB4.
 
 0.961
dotD
Lipoprotein DotD.
    
 
 0.945
Lfee_2292
IcmJ protein.
 
   
 0.943
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: low (14%) [HD]