Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lphALphA (DotK). (191 aa)    
Predicted Functional Partners:
spkB_3
Protein IcmE (DotG).
 
 
 
 0.973
Lfee_2785
Outer membrane protein, OmpA family protein.
  
 
   0.970
Lfee_2297
IcmK protein.
   
   0.966
Lfee_2295
Protein IcmG (DotF).
   
   0.961
icmM/dotJ
Component of the Dot/Icm secretion system, predicted inner membrane protein.
     
 0.859
Lfee_2298
Protein IcmL (DotI).
     
 0.854
Lfee_1743
Major outer membrane protein.
    
   0.826
Lfee_2878
Major outer membrane protein.
    
   0.826
Lfee_2294
IcmC (DotE).
       0.820
icmD_2
Protein IcmD (DotP).
       0.801
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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