Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
emrB_1Multidrug resistance protein, MFS superfamily. (508 aa)    
Predicted Functional Partners:
emrA_2
Multidrug efflux system.
 
   0.971
mdtP_1
Outer membrane efflux lipoprotein.
 
 
   0.934
emrA_1
Multidrug efflux system.
 
   0.816
yibH
Multidrug resistance protein.
 
   0.781
emrA_2-2
Hemolysin D.
  
   0.780
Lfee_2370
Hypothetical protein.
       0.457
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
     
  0.436
trpE
Anthranilate synthase.
     
  0.413
mdtP_2
Outer membrane efflux protein.
 
 
   0.410
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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