pdxJ protein (Legionella feeleii) - STRING interaction network

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pdxJ

Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (248 aa)

Predicted Functional Partners:

pdxH

0.964

pdxH_2

0.922

pdxH_1

0.921

pdxA

0.902

korA

0.892

Lfee_2568

0.860

recO

0.851

era

0.748

pdxB

0.672

ribA

0.671

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_2568	era	Lfee_2568	Lfee_2572	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.694
Lfee_2568	korA	Lfee_2568	Lfee_2569	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.999
Lfee_2568	pdxB	Lfee_2568	Lfee_2632	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.	0.467
Lfee_2568	pdxJ	Lfee_2568	Lfee_2570	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.860
Lfee_2568	recO	Lfee_2568	Lfee_2571	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.	0.694
era	Lfee_2568	Lfee_2572	Lfee_2568	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.694
era	korA	Lfee_2572	Lfee_2569	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.698
era	pdxJ	Lfee_2572	Lfee_2570	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.748
era	recO	Lfee_2572	Lfee_2571	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.	0.927
korA	Lfee_2568	Lfee_2569	Lfee_2568	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.999
korA	era	Lfee_2569	Lfee_2572	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.698
korA	pdxB	Lfee_2569	Lfee_2632	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.	0.838
korA	pdxJ	Lfee_2569	Lfee_2570	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.892
korA	recO	Lfee_2569	Lfee_2571	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.	0.701
pdxA	pdxB	Lfee_3190	Lfee_2632	4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).	Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.	0.702
pdxA	pdxJ	Lfee_3190	Lfee_2570	4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).	Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.902
pdxA	ribA	Lfee_3190	Lfee_1116	4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).	Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.671
pdxB	Lfee_2568	Lfee_2632	Lfee_2568	Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.467
pdxB	korA	Lfee_2632	Lfee_2569	Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.838
pdxB	pdxA	Lfee_2632	Lfee_3190	Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.	4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).	0.702

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