Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Lfee_2692IcmX (IcmY). (454 aa)    
Predicted Functional Partners:
dotA
Defect in organelle trafficking protein DotA.
   
   0.943
icmW
Intracellular multiplication protein IcmW.
     
 0.942
spkB_3
Protein IcmE (DotG).
    
 
 0.940
icmV
Intracellular multiplication protein IcmV.
     
 0.896
Lfee_2295
Protein IcmG (DotF).
    
 
 0.834
Lfee_2297
IcmK protein.
    
 
 0.810
htpB
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.607
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.607
Lfee_2130
IcmF.
      
 0.607
Lfee_2302
IcmP protein.
      
 0.607
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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