Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
Lfee_2699Protein-tyrosine phosphatase. (233 aa)    
Predicted Functional Partners:
spkB_3
Protein IcmE (DotG).
  
     0.746
dotA
Defect in organelle trafficking protein DotA.
  
     0.737
Lfee_0606
Putative membrane protein YdgA-like protein.
  
     0.731
Lfee_3232
Secreted protein.
  
     0.726
Lfee_2162
Zip family transporter.
  
     0.706
Lfee_1773
Putative helicase/relaxase.
  
     0.698
Lfee_2130
IcmF.
  
     0.671
ung
Uracil DNA glycosylase; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
  
     0.659
enhC
Enhanced entry protein EnhC.
  
     0.625
epsL
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.619
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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