Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lfee_2743Nitropropane dioxygenase/trans-enoyl-CoA reductase. (352 aa)    
Predicted Functional Partners:
Lfee_1859
Polyketide synthase module.
  
 0.823
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.795
tycC_2
Peptide synthetase, non-ribosomal.
  
 0.781
sspH2
Leucine rich repeat protein.
       0.773
coxB
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
     
  0.755
fabD
Malonyl CoA-ACP transacylase.
  
 
 0.754
psf-1
Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
  
 
 0.678
Lfee_2374
Acetyltransferase.
  
 0.672
fabF_1
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.666
fabF_2
3-oxoacyl-ACP synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.666
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: low (14%) [HD]