| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lfee_2374 | bioA | Lfee_2374 | Lfee_2943 | Acetyltransferase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.656 |
| Lfee_2374 | bioC | Lfee_2374 | Lfee_2099 | Acetyltransferase. | Biotin synthase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.604 |
| Lfee_2374 | bioH | Lfee_2374 | Lfee_2940 | Acetyltransferase. | Biotin biosynthesis protein BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.852 |
| Lfee_2374 | cheY | Lfee_2374 | Lfee_1387 | Acetyltransferase. | Sensory histidine-kinase / response regulator. | 0.909 |
| Lfee_2374 | cqsA | Lfee_2374 | Lfee_2757 | Acetyltransferase. | Aminotransferase class II. | 0.882 |
| Lfee_2374 | pksJ | Lfee_2374 | Lfee_0647 | Acetyltransferase. | Polyketide synthase module. | 0.996 |
| Lfee_2374 | tycC_2 | Lfee_2374 | Lfee_0691 | Acetyltransferase. | Peptide synthetase, non-ribosomal. | 0.997 |
| bioA | Lfee_2374 | Lfee_2943 | Lfee_2374 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyltransferase. | 0.656 |
| bioA | bioB | Lfee_2943 | Lfee_2942 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.999 |
| bioA | bioC | Lfee_2943 | Lfee_2099 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.814 |
| bioA | bioD | Lfee_2943 | Lfee_2939 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioA | bioH | Lfee_2943 | Lfee_2940 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin biosynthesis protein BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.911 |
| bioA | cqsA | Lfee_2943 | Lfee_2757 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aminotransferase class II. | 0.853 |
| bioA | pksJ | Lfee_2943 | Lfee_0647 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Polyketide synthase module. | 0.620 |
| bioA | tycC_2 | Lfee_2943 | Lfee_0691 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Peptide synthetase, non-ribosomal. | 0.833 |
| bioB | bioA | Lfee_2942 | Lfee_2943 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.999 |
| bioB | bioC | Lfee_2942 | Lfee_2099 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin synthase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.982 |
| bioB | bioD | Lfee_2942 | Lfee_2939 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioB | bioH | Lfee_2942 | Lfee_2940 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin biosynthesis protein BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.925 |
| bioB | cqsA | Lfee_2942 | Lfee_2757 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Aminotransferase class II. | 0.752 |