STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garR_23-hydroxyisobutyrate dehydrogenase. (290 aa)    
Predicted Functional Partners:
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.810
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.810
Lfee_1322
Acetyltransferase Pat.
    
  0.719
garR_1
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.670
Lfee_1304
Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
 
  0.619
Lfee_2813
Hypothetical protein; RecF/RecN/SMC N terminal domain.
       0.541
pdxB
Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
    
  0.540
nfdA
N-substituted formamide deformylase precursor.
 
  
  0.539
qorA
Quinone oxidoreductase.
  
  
  0.526
qor_1
Quinone oxidoreductase (NADPH:quinone reductase).
  
  
  0.522
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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