STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)    
Predicted Functional Partners:
ydiA
Putative phosphotransferase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.903
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
     
 0.846
cfiA_1
Oxaloacetate decarboxylase subunit alpha.
  
 
 0.829
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.827
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
    
 0.826
Lfee_2888
Succinyl-diaminopimelate desuccinylase.
       0.800
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
       0.800
nadC
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
       0.800
yhaU
Na(+)/H(+) antiporter.
       0.800
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.732
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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