Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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ydfGNADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)    
Predicted Functional Partners:
grsB
Non-ribosomal peptide synthetase.
   
  0.943
ltaE
Low specificity L-threonine aldolase.
    
 0.855
tdh
Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
    
  0.843
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
     
  0.843
tycC_1
Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
  0.746
pksJ
Polyketide synthase module.
  
 
 0.735
gcsB
Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
 
      0.702
tycC_2
Peptide synthetase, non-ribosomal.
 
 
  0.664
merA1
Mercuric reductase.
       0.658
pdxH_2
Pyridoxamine 5'-phosphate oxidase.
  
    0.613
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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