Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
merA1Mercuric reductase. (242 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoyl dehydrogenase.
      0.895
gor
Glutathione reductase.
    
 0.884
ydfG
NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.658
Lfee_2374
Acetyltransferase.
    
 0.535
aas_2
2-acylglycerophosphoethanolamine acyltransferase.
    
  0.520
aas_1
2-acylglycerophosphoethanolamine acyltransferase.
    
  0.520
Lfee_0704
Putative Ser/Thr protein kinase.
 
     0.473
pdxH_2
Pyridoxamine 5'-phosphate oxidase.
       0.460
Lfee_2926
Hypothetical protein.
       0.442
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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