Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lfee_3046Ankyrin repeats (3 copies). (404 aa)    
Predicted Functional Partners:
Lfee_1930
Ankyrin repeat-containing protein.
  
     0.764
Lfee_2486
Ankyrin repeat-containing protein.
  
     0.757
Lfee_0449
Ankyrin repeat protein.
  
     0.753
Lfee_1678
Methyltransferase.
 
 
  0.611
metG
Methionyl tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
  0.577
yrrB
Methyltransferase.
 
 
  0.570
Lfee_2483
SET domain protein.
  
 
  0.568
arp
Ankyrin repeat domain-containing protein.
  
     0.527
sahH
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.518
Lfee_3045
Coenzyme F390 synthetase.
       0.514
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: low (28%) [HD]