Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ygfZGlycine cleavage T protein. (322 aa)    
Predicted Functional Partners:
yadR
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 
 
 0.804
cptB
Antitoxin CptB.
 
     0.804
Lfee_3070
Hypothetical protein.
       0.753
rpoE
Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.
       0.693
sufA
Fe-S cluster assembly protein; Belongs to the HesB/IscA family.
   
 
 0.651
tolA
TolA colicin import membrane protein.
 
     0.634
Lfee_0745
Hypothetical protein.
  
     0.620
damX
DamX-related protein.
  
     0.617
Lfee_2672
Type II/III secretion system protein.
  
     0.611
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.611
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: medium (44%) [HD]