miaE protein (Legionella feeleii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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co-expression

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gene co-occurrence

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[Homology]

Score

miaE

tRNA hydroxylase. (206 aa)

Predicted Functional Partners:

Lfee_3091

0.752

yfgB

0.745

ndk

0.685

hisS

0.612

Lfee_3097

0.597

miaB

0.578

sdhD

0.553

miaA

0.516

yrbA

0.430

rodZ

0.429

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_3091	Lfee_3097	Lfee_3091	Lfee_3097	Hypothetical protein.	Transmembrane protein.	0.680
Lfee_3091	hisS	Lfee_3091	Lfee_3096	Hypothetical protein.	histidyl-tRNA synthetase.	0.686
Lfee_3091	miaE	Lfee_3091	Lfee_3090	Hypothetical protein.	tRNA hydroxylase.	0.752
Lfee_3091	ndk	Lfee_3091	Lfee_3092	Hypothetical protein.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.757
Lfee_3091	rodZ	Lfee_3091	Lfee_3095	Hypothetical protein.	DNA-binding protein.	0.664
Lfee_3091	yfgB	Lfee_3091	Lfee_3093	Hypothetical protein.	Fe-S containing enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.	0.736
Lfee_3097	Lfee_3091	Lfee_3097	Lfee_3091	Transmembrane protein.	Hypothetical protein.	0.680
Lfee_3097	hisS	Lfee_3097	Lfee_3096	Transmembrane protein.	histidyl-tRNA synthetase.	0.979
Lfee_3097	miaE	Lfee_3097	Lfee_3090	Transmembrane protein.	tRNA hydroxylase.	0.597
Lfee_3097	ndk	Lfee_3097	Lfee_3092	Transmembrane protein.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.759
Lfee_3097	rodZ	Lfee_3097	Lfee_3095	Transmembrane protein.	DNA-binding protein.	0.884
Lfee_3097	yfgB	Lfee_3097	Lfee_3093	Transmembrane protein.	Fe-S containing enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.	0.772
hisS	Lfee_3091	Lfee_3096	Lfee_3091	histidyl-tRNA synthetase.	Hypothetical protein.	0.686
hisS	Lfee_3097	Lfee_3096	Lfee_3097	histidyl-tRNA synthetase.	Transmembrane protein.	0.979
hisS	miaE	Lfee_3096	Lfee_3090	histidyl-tRNA synthetase.	tRNA hydroxylase.	0.612
hisS	ndk	Lfee_3096	Lfee_3092	histidyl-tRNA synthetase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.779
hisS	rodZ	Lfee_3096	Lfee_3095	histidyl-tRNA synthetase.	DNA-binding protein.	0.872
hisS	yfgB	Lfee_3096	Lfee_3093	histidyl-tRNA synthetase.	Fe-S containing enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.	0.806
miaA	miaB	Lfee_2707	Lfee_3006	tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.	(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.	0.866
miaA	miaE	Lfee_2707	Lfee_3090	tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.	tRNA hydroxylase.	0.516