Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolCBIolC/IolB transferase kinase protein; Belongs to the carbohydrate kinase PfkB family. (354 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde-2,1-aminomutase.
     
 0.860
cpsB
Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.841
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.826
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.824
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
  
    0.788
rubR
Rubredoxin.
       0.741
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.671
sodB
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 
 0.669
Lfee_0057
SMP-30/Gluconolaconase/LRE-like region.
     
 0.661
rpe
D-ribulose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.661
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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