| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lfee_2003 | aroC | Lfee_2003 | Lfee_2253 | Aspartate aminotransferase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.499 |
| Lfee_2003 | gcvT | Lfee_2003 | Lfee_1708 | Aspartate aminotransferase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.447 |
| Lfee_2003 | glyA | Lfee_2003 | Lfee_0067 | Aspartate aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.487 |
| Lfee_2003 | hisC | Lfee_2003 | Lfee_0927 | Aspartate aminotransferase. | Histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.576 |
| Lfee_2003 | mnmC | Lfee_2003 | Lfee_3112 | Aspartate aminotransferase. | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.687 |
| Lfee_2003 | pheA_1 | Lfee_2003 | Lfee_1459 | Aspartate aminotransferase. | P-protein. | 0.758 |
| Lfee_2003 | pheA_2 | Lfee_2003 | Lfee_2044 | Aspartate aminotransferase. | Prephenate dehydratase. | 0.758 |
| Lfee_2003 | trpE | Lfee_2003 | Lfee_0942 | Aspartate aminotransferase. | Anthranilate synthase. | 0.840 |
| Lfee_2003 | yfdZ | Lfee_2003 | Lfee_2955 | Aspartate aminotransferase. | Aminotransferase. | 0.651 |
| aroC | Lfee_2003 | Lfee_2253 | Lfee_2003 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aspartate aminotransferase. | 0.499 |
| aroC | hisC | Lfee_2253 | Lfee_0927 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.710 |
| aroC | mnmC | Lfee_2253 | Lfee_3112 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.677 |
| aroC | pheA_1 | Lfee_2253 | Lfee_1459 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | P-protein. | 0.937 |
| aroC | pheA_2 | Lfee_2253 | Lfee_2044 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Prephenate dehydratase. | 0.938 |
| aroC | trpE | Lfee_2253 | Lfee_0942 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase. | 0.866 |
| aroC | yfdZ | Lfee_2253 | Lfee_2955 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminotransferase. | 0.499 |
| dtpB_1 | mnmC | Lfee_3111 | Lfee_3112 | Peptide transport protein, POT family. | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.681 |
| gcvT | Lfee_2003 | Lfee_1708 | Lfee_2003 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Aspartate aminotransferase. | 0.447 |
| gcvT | glyA | Lfee_1708 | Lfee_0067 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.989 |
| gcvT | mnmC | Lfee_1708 | Lfee_3112 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.932 |
STRING v12.5 is now available!
