Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gloBHydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (254 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase.
 
 
 0.983
rlmJ
Protein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA.
       0.790
mltD
Membrane bound lytic murein transglycosylase D.
       0.725
Lfee_3202
Hypothetical protein.
       0.678
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
  
   
 0.639
hchA
Intracellular protease/amidase.
    
 0.637
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
   
  
 0.586
dprE1_1
Hypothetical protein.
     
  0.549
grlA
Glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
   
 0.511
Lfee_0518
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
   
 
  0.499
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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