| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lfee_3263 | parA_5 | Lfee_3263 | Lfee_3264 | Hypothetical protein. | Sporulation initiation inhibitor protein Soj. | 0.727 |
| birA | dnaA | Lfee_1087 | Lfee_1818 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.410 |
| birA | ftsK | Lfee_1087 | Lfee_3037 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Cell division protein FtsK. | 0.406 |
| birA | parA_3 | Lfee_1087 | Lfee_2869 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Sporulation initiation inhibitor protein Soj. | 0.502 |
| birA | parA_4 | Lfee_1087 | Lfee_3244 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Chromosome partitioning protein ParA. | 0.502 |
| birA | parA_5 | Lfee_1087 | Lfee_3264 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Sporulation initiation inhibitor protein Soj. | 0.502 |
| dnaA | birA | Lfee_1818 | Lfee_1087 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.410 |
| dnaA | ftsK | Lfee_1818 | Lfee_3037 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Cell division protein FtsK. | 0.576 |
| dnaA | parA_3 | Lfee_1818 | Lfee_2869 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Sporulation initiation inhibitor protein Soj. | 0.492 |
| dnaA | parA_4 | Lfee_1818 | Lfee_3244 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Chromosome partitioning protein ParA. | 0.475 |
| dnaA | parA_5 | Lfee_1818 | Lfee_3264 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Sporulation initiation inhibitor protein Soj. | 0.477 |
| dnaA | parB_1 | Lfee_1818 | Lfee_0293 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Chromosome partitioning protein parB; Belongs to the ParB family. | 0.445 |
| dnaA | xerC_2 | Lfee_1818 | Lfee_3271 | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Hypothetical protein; Belongs to the 'phage' integrase family. | 0.463 |
| ftsK | birA | Lfee_3037 | Lfee_1087 | Cell division protein FtsK. | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.406 |
| ftsK | dnaA | Lfee_3037 | Lfee_1818 | Cell division protein FtsK. | Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.576 |
| ftsK | parA_3 | Lfee_3037 | Lfee_2869 | Cell division protein FtsK. | Sporulation initiation inhibitor protein Soj. | 0.599 |
| ftsK | parA_4 | Lfee_3037 | Lfee_3244 | Cell division protein FtsK. | Chromosome partitioning protein ParA. | 0.410 |
| ftsK | parA_5 | Lfee_3037 | Lfee_3264 | Cell division protein FtsK. | Sporulation initiation inhibitor protein Soj. | 0.606 |
| ftsK | parB_1 | Lfee_3037 | Lfee_0293 | Cell division protein FtsK. | Chromosome partitioning protein parB; Belongs to the ParB family. | 0.759 |
| ftsK | parB_2 | Lfee_3037 | Lfee_0555 | Cell division protein FtsK. | Chromosome partitioning protein ParB; Belongs to the ParB family. | 0.762 |