node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OAN58879.1 | OAN61638.1 | A7X12_04365 | A7X12_23345 | Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
OAN58879.1 | dut | A7X12_04365 | A7X12_10900 | Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.649 |
OAN58879.1 | tdk | A7X12_04365 | A7X12_12965 | Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
OAN58879.1 | thyA | A7X12_04365 | A7X12_04385 | Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.998 |
OAN61540.1 | OAN61637.1 | A7X12_23340 | A7X12_23335 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
OAN61540.1 | OAN61638.1 | A7X12_23340 | A7X12_23345 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
OAN61637.1 | OAN61540.1 | A7X12_23335 | A7X12_23340 | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
OAN61637.1 | OAN61638.1 | A7X12_23335 | A7X12_23345 | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.630 |
OAN61638.1 | OAN58879.1 | A7X12_23345 | A7X12_04365 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.670 |
OAN61638.1 | OAN61540.1 | A7X12_23345 | A7X12_23340 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
OAN61638.1 | OAN61637.1 | A7X12_23345 | A7X12_23335 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.630 |
OAN61638.1 | OAN67273.1 | A7X12_23345 | A7X12_00405 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.650 |
OAN61638.1 | adk | A7X12_23345 | A7X12_04960 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.691 |
OAN61638.1 | coaX | A7X12_23345 | A7X12_21395 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.665 |
OAN61638.1 | dut | A7X12_23345 | A7X12_10900 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.619 |
OAN61638.1 | ndk | A7X12_23345 | A7X12_02525 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.652 |
OAN61638.1 | tdk | A7X12_23345 | A7X12_12965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.693 |
OAN61638.1 | thyA | A7X12_23345 | A7X12_04385 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.699 |
OAN67273.1 | OAN61638.1 | A7X12_00405 | A7X12_23345 | Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.650 |
OAN67273.1 | tdk | A7X12_00405 | A7X12_12965 | Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |