STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANJ28433.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family. (518 aa)    
Predicted Functional Partners:
ANJ28432.1
IMP dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.632
ANJ27485.1
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.570
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
  0.545
ANJ28434.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
ANJ26431.1
ATP-dependent RNA helicase HrpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.538
ANJ26878.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.510
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.509
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.501
rpsA
30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.496
ANJ28431.1
Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.413
Your Current Organism:
Agromyces aureus
NCBI taxonomy Id: 453304
Other names: A. aureus, Agromyces aureus Corretto et al. 2016, Agromyces sp. AR33, DSM 101731, LMG 29235, LMG:29235, strain AR33
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