STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
v1g238590Predicted protein. (889 aa)    
Predicted Functional Partners:
v1g214346
Predicted protein.
  
0.998
v1g82384
Predicted protein.
 
 0.920
v1g88316
Predicted protein.
 
 0.891
v1g167864
Predicted protein.
  
 0.874
v1g199930
Predicted protein.
  
 0.836
v1g246770
Predicted protein.
  
 0.828
v1g231142
Predicted protein.
  
 0.828
v1g108642
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.785
v1g63961
Predicted protein.
  
 0.767
v1g124403
Predicted protein.
   
  
 0.710
Your Current Organism:
Nematostella vectensis
NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone
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