STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
v1g105108Predicted protein. (195 aa)    
Predicted Functional Partners:
v1g31023
Predicted protein.
    
 0.986
v1g243338
Predicted protein.
   
  
 0.651
v1g164009
Predicted protein.
      
 0.617
v1g160437
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 
 0.531
v1g190967
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 
 0.531
v1g61368
Predicted protein.
      
 0.513
v1g211400
Cyclic GMP-AMP synthase; Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Acts as a key cytosolic DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses (By similarity). Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to a [...]
      
 0.493
v1g244707
Predicted protein.
    
 0.479
v1g143444
Predicted protein.
    
 0.479
v1g248767
Predicted protein.
    
 0.479
Your Current Organism:
Nematostella vectensis
NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.