STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
v1g174598Predicted protein. (714 aa)    
Predicted Functional Partners:
v1g84034
Predicted protein.
   
 
 0.967
v1g108642
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.948
v1g12162
Predicted protein.
  
 0.938
v1g133840
Predicted protein.
   
 0.919
v1g224077
Predicted protein.
 
      0.899
v1g167864
Predicted protein.
  
 0.865
v1g233970
DNA polymerase.
   
 0.850
v1g79419
Predicted protein.
   
 
 0.829
v1g211009
Predicted protein.
  
 0.824
v1g237900
Predicted protein.
    
 0.807
Your Current Organism:
Nematostella vectensis
NCBI taxonomy Id: 45351
Other names: N. vectensis, starlet sea anemone
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