STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXQ85_003539Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (481 aa)    
Predicted Functional Partners:
CXQ85_000290
Autophagy-related protein.
   
 0.994
CXQ85_003409
Protein kinase domain-containing protein.
   
 
 0.972
CXQ85_000743
Lipase_3 domain-containing protein.
   
 
 0.965
CXQ85_001603
Autophagy-related protein 3.
   
 
 0.727
CXQ85_002444
Uncharacterized protein.
   
 
 0.703
CXQ85_000495
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 
 0.656
CXQ85_004020
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 
 0.606
CXQ85_001785
Uncharacterized protein.
    
 
 0.601
CXQ85_001149
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 
 0.562
CXQ85_005246
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.553
Your Current Organism:
Candida haemulonis
NCBI taxonomy Id: 45357
Other names: ATCC 22991, CBS 5149, Candida haemulonii type II, DBVPG 6958, IFO 10001, IGC 3025, JCM 3762, NRRL Y-6693, Torulopsis haemuloni, [. haemulonis, [Candida] haemulonis
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