Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Igni_0788PFAM: sugar isomerase (SIS). (201 aa)    
Predicted Functional Partners:
Igni_0269
PFAM: Orotidine 5'-phosphate decarboxylase.
 
 0.999
Igni_0415
PFAM: glucose-6-phosphate isomerase.
 
 
  0.931
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
 0.907
Igni_0891
Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein.
    
  0.900
Igni_1267
PFAM: Transketolase domain protein.
    
  0.900
Igni_0789
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.789
Igni_0628
PFAM: oxidoreductase domain protein; Alcohol dehydrogenase, zinc-binding domain protein.
  
    0.678
Igni_0786
Dinucleotide-utilizing enzyme-like protein.
       0.664
Igni_0787
TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71, ATP-binding region.
       0.664
Igni_0785
Hypothetical protein.
       0.566
Your Current Organism:
Ignicoccus hospitalis
NCBI taxonomy Id: 453591
Other names: I. hospitalis KIN4/I, Ignicoccus hospitalis DSM 18386, Ignicoccus hospitalis JCM 14125, Ignicoccus hospitalis KIN4/I, Ignicoccus hospitalis str. KIN4/I, Ignicoccus hospitalis strain KIN4/I
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.