STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (360 aa)    
Predicted Functional Partners:
Igni_0566
PFAM: aspartate/glutamate/uridylate kinase.
 
  
 0.981
Igni_1168
PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.960
Igni_0946
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase.
  
 0.834
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
  
 0.827
Igni_1097
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.
  
 
 0.756
Igni_0628
PFAM: oxidoreductase domain protein; Alcohol dehydrogenase, zinc-binding domain protein.
  
  
 0.733
Igni_0992
PFAM: protein of unknown function DUF52; Belongs to the MEMO1 family.
  
    0.718
Igni_0002
PFAM: FAD linked oxidase domain protein.
  
 0.717
rps2
PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.709
Igni_1167
Hypothetical protein.
       0.708
Your Current Organism:
Ignicoccus hospitalis
NCBI taxonomy Id: 453591
Other names: I. hospitalis KIN4/I, Ignicoccus hospitalis DSM 18386, Ignicoccus hospitalis JCM 14125, Ignicoccus hospitalis KIN4/I, Ignicoccus hospitalis str. KIN4/I, Ignicoccus hospitalis strain KIN4/I
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