Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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Score
Igni_0892TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein. (348 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.999
Igni_0307
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein.
 
 
 0.998
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.996
Igni_1333
Histidinol phosphate aminotransferase; PFAM: aminotransferase, class I and II.
  
 
 0.995
Igni_0406
PFAM: aminotransferase, class I and II.
  
 
 0.994
Igni_0466
Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
  
 
 0.994
Igni_0925
PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein.
  
 
 0.993
Igni_1436
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA.
  
  
 0.982
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
  
 0.978
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.977
Your Current Organism:
Ignicoccus hospitalis
NCBI taxonomy Id: 453591
Other names: I. hospitalis KIN4/I, Ignicoccus hospitalis DSM 18386, Ignicoccus hospitalis JCM 14125, Ignicoccus hospitalis KIN4/I, Ignicoccus hospitalis str. KIN4/I, Ignicoccus hospitalis strain KIN4/I
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