node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Igni_0062 | Igni_0250 | Igni_0062 | Igni_0250 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | 0.731 |
Igni_0062 | Igni_0690 | Igni_0062 | Igni_0690 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.926 |
Igni_0062 | Igni_0953 | Igni_0062 | Igni_0953 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type. | 0.755 |
Igni_0062 | Igni_1295 | Igni_0062 | Igni_1295 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | 0.731 |
Igni_0062 | Igni_1297 | Igni_0062 | Igni_1297 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | Replicative DNA helicase Mcm; PFAM: MCM family protein; ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; Belongs to the MCM family. | 0.948 |
Igni_0062 | fen | Igni_0062 | Igni_0691 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.913 |
Igni_0062 | priL | Igni_0062 | Igni_0078 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.950 |
Igni_0062 | priS | Igni_0062 | Igni_0855 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.954 |
Igni_0062 | rfcL | Igni_0062 | Igni_1300 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.765 |
Igni_0062 | rfcS | Igni_0062 | Igni_1299 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.795 |
Igni_0250 | Igni_0062 | Igni_0250 | Igni_0062 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.731 |
Igni_0250 | Igni_0690 | Igni_0250 | Igni_0690 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.754 |
Igni_0250 | Igni_0953 | Igni_0250 | Igni_0953 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type. | 0.745 |
Igni_0250 | Igni_1295 | Igni_0250 | Igni_1295 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | 0.644 |
Igni_0250 | Igni_1297 | Igni_0250 | Igni_1297 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | Replicative DNA helicase Mcm; PFAM: MCM family protein; ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; Belongs to the MCM family. | 0.969 |
Igni_0250 | fen | Igni_0250 | Igni_0691 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.632 |
Igni_0250 | priL | Igni_0250 | Igni_0078 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.899 |
Igni_0250 | priS | Igni_0250 | Igni_0855 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.850 |
Igni_0250 | rfcL | Igni_0250 | Igni_1300 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.440 |
Igni_0250 | rfcS | Igni_0250 | Igni_1299 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. | 0.525 |