Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CAT05061.1HYPOTHETICAL PROTEIN. (423 aa)    
Predicted Functional Partners:
pdhD
Dihydrolipoamide dehydrogenase.
  
 0.961
dnaJ
Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
   0.836
ftsH_3
AAA family ATPase; Belongs to the AAA ATPase family.
  
 
 0.834
pdhB
Pyruvate dehydrogenase.
   
  0.817
glpF
Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.810
prsA
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.711
pdhC
Dihydrolipoamide acetyltransferase.
   
  0.708
CAT04938.1
HYPOTHETICAL PROTEIN.
  
 
 0.675
pdhA
Pyruvate dehydrogenase E1-alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
  0.645
pdhD-1
Dihydrolipoamide dehydrogenase.
  
  0.621
Your Current Organism:
Mycoplasma conjunctivae
NCBI taxonomy Id: 45361
Other names: ATCC 25834, M. conjunctivae, Mesomycoplasma conjunctivae, NCTC 10147, strain HRC/583
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