Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gcvHGlycine cleavage system H protein. (111 aa)    
Predicted Functional Partners:
pdhD
Dihydrolipoamide dehydrogenase.
  
 0.971
lplA-2
Lipoate-protein ligase.
   
 0.959
pdhD-1
Dihydrolipoamide dehydrogenase.
   
 0.870
CAT05110.1
HYPOTHETICAL PROTEIN.
  
  
 0.855
CAT05108.1
OXYGENASE.
     
 0.824
baiH
NADH-dependent flavin oxidoreductase.
       0.821
lplA
Lipoate-protein ligase A.
   
 0.802
acpP_1
PUTATIVE Acyl carrier protein homolog.
  
 
 0.770
pdhC
Dihydrolipoamide acetyltransferase.
  
 0.731
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.577
Your Current Organism:
Mycoplasma conjunctivae
NCBI taxonomy Id: 45361
Other names: ATCC 25834, M. conjunctivae, Mesomycoplasma conjunctivae, NCTC 10147, strain HRC/583
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