Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (673 aa)    
Predicted Functional Partners:
cbiO1
Cobalt import ATP-binding protein cbiO 1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
       0.821
cbiO2
Cobalt import ATP-binding protein cbiO 2; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
       0.821
ecfT_1
ABC TRANSPORTER PERMEASE PROTEIN.
       0.821
polA_1
5-3 exonuclease.
 
   
 0.677
CAT05174.1
HYPOTHETICAL Uncharacterized protein UU046.
  
    0.638
dnaX
DNA polymerase III gamma and tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
     
 0.615
polC
DNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
  
 0.612
pcrA
ATP-dependent helicase PcrA.
  
  
 0.602
dnaE
DNA polymerase III alpha subunit.
     
 0.599
leuS
Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.585
Your Current Organism:
Mycoplasma conjunctivae
NCBI taxonomy Id: 45361
Other names: ATCC 25834, M. conjunctivae, Mesomycoplasma conjunctivae, NCTC 10147, strain HRC/583
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