pdhD-1 protein (Mycoplasma conjunctivae) - STRING interaction network

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Score

pdhD-1

Dihydrolipoamide dehydrogenase. (454 aa)

Predicted Functional Partners:

pdhB

0.993

pdhC

0.991

pdhD

0.988

pdhA

0.980

glyA

0.923

gcvH

0.870

prsA

0.808

lplA

0.787

lplA-2

0.723

fruA

0.699

Your Current Organism:

Mycoplasma conjunctivae

NCBI taxonomy Id: 45361
Other names: ATCC 25834, M. conjunctivae, Mesomycoplasma conjunctivae, NCTC 10147, strain HRC/583

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fruA	pdhA	MCJ_005330	MCJ_000670	PTS system, fructose-specific IIABC component.	Pyruvate dehydrogenase E1-alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.530
fruA	pdhB	MCJ_005330	MCJ_000680	PTS system, fructose-specific IIABC component.	Pyruvate dehydrogenase.	0.501
fruA	pdhC	MCJ_005330	MCJ_000690	PTS system, fructose-specific IIABC component.	Dihydrolipoamide acetyltransferase.	0.468
fruA	pdhD	MCJ_005330	MCJ_000700	PTS system, fructose-specific IIABC component.	Dihydrolipoamide dehydrogenase.	0.671
fruA	pdhD-1	MCJ_005330	MCJ_005300	PTS system, fructose-specific IIABC component.	Dihydrolipoamide dehydrogenase.	0.699
fruA	prsA	MCJ_005330	MCJ_000270	PTS system, fructose-specific IIABC component.	Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.	0.763
gcvH	glyA	MCJ_004190	MCJ_005830	Glycine cleavage system H protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.577
gcvH	lplA	MCJ_004190	MCJ_003870	Glycine cleavage system H protein.	Lipoate-protein ligase A.	0.802
gcvH	lplA-2	MCJ_004190	MCJ_004210	Glycine cleavage system H protein.	Lipoate-protein ligase.	0.959
gcvH	pdhC	MCJ_004190	MCJ_000690	Glycine cleavage system H protein.	Dihydrolipoamide acetyltransferase.	0.731
gcvH	pdhD	MCJ_004190	MCJ_000700	Glycine cleavage system H protein.	Dihydrolipoamide dehydrogenase.	0.971
gcvH	pdhD-1	MCJ_004190	MCJ_005300	Glycine cleavage system H protein.	Dihydrolipoamide dehydrogenase.	0.870
glyA	gcvH	MCJ_005830	MCJ_004190	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine cleavage system H protein.	0.577
glyA	pdhD	MCJ_005830	MCJ_000700	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Dihydrolipoamide dehydrogenase.	0.959
glyA	pdhD-1	MCJ_005830	MCJ_005300	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Dihydrolipoamide dehydrogenase.	0.923
glyA	prsA	MCJ_005830	MCJ_000270	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.	0.435
lplA	gcvH	MCJ_003870	MCJ_004190	Lipoate-protein ligase A.	Glycine cleavage system H protein.	0.802
lplA	lplA-2	MCJ_003870	MCJ_004210	Lipoate-protein ligase A.	Lipoate-protein ligase.	0.924
lplA	pdhA	MCJ_003870	MCJ_000670	Lipoate-protein ligase A.	Pyruvate dehydrogenase E1-alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.402
lplA	pdhB	MCJ_003870	MCJ_000680	Lipoate-protein ligase A.	Pyruvate dehydrogenase.	0.573