STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lisr_02823-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)    
Predicted Functional Partners:
Lisr_0528
Acetoacetate decarboxylase.
 
  
  0.963
Lisr_0281
Alpha-beta hydrolase family transporter esterase.
 
 
   0.920
acsA
acetyl-CoA synthetase.
    
 0.903
mvaB
hydroxymethylglutaryl-CoA lyase.
   
 
  0.901
Lisr_2325
O-methyltransferase.
 
  
 
 0.799
Lisr_0004
Hypothetical protein.
  
 
 0.678
yueD
Sepiapterin reductase.
  
     0.649
Lisr_0283
Glycine zipper 2TM domain protein.
       0.499
Lisr_0799
Alkaline phosphatase.
   
 
 0.475
Lisr_1592
Putative Sulfatase.
   
 
 0.475
Your Current Organism:
Legionella israelensis
NCBI taxonomy Id: 454
Other names: ATCC 43119, CCUG 31115, CIP 103879, DSM 19235, JCM 7560, L. israelensis, NCTC 12010, strain Bercovier 4
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