STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vdh_1Vitamin D(3) 25-hydroxylase; Belongs to the cytochrome P450 family. (116 aa)    
Predicted Functional Partners:
Lisr_0004
Hypothetical protein.
  
 0.977
Lisr_1179
Peptide synthetase, non-ribosomal.
  
 0.941
Lisr_2652
Peptide synthetase.
  
 0.919
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
    
 0.893
Lisr_0001
Polyketide synthase module.
 
 0.863
Lisr_1610
Non-ribosomal peptide synthetase/polyketide synthetase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.859
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.763
Lisr_1533
FAD dependent oxidoreductase.
 
 
 0.725
Lisr_1780
Nitroreductase.
       0.682
Lisr_1787
Ferredoxin reductase.
  
 0.634
Your Current Organism:
Legionella israelensis
NCBI taxonomy Id: 454
Other names: ATCC 43119, CCUG 31115, CIP 103879, DSM 19235, JCM 7560, L. israelensis, NCTC 12010, strain Bercovier 4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.