STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASPCAL08050Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (340 aa)    
Predicted Functional Partners:
ASPCAL06191
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 0.999
ASPCAL05878
Autophagy-related protein 3.
   
 0.998
ASPCAL04398
Putative WD repeat domain phosphoinositide-interacting protein.
    
 0.995
ASPCAL08119
Autophagy-related protein.
   
 0.989
ASPCAL11726
Putative Serine/threonine-protein kinase atg1.
    
 
 0.989
ASPCAL11070
Uncharacterized protein.
    
 0.985
ASPCAL04442
ATG16 domain-containing protein.
   
 0.981
ASPCAL08221
Uncharacterized protein.
   
 0.977
ASPCAL05486
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.942
ASPCAL00978
Putative Lipase Atg15.
   
 
 0.941
Your Current Organism:
Aspergillus calidoustus
NCBI taxonomy Id: 454130
Other names: A. calidoustus, Aspergillus calidoustus Varga, Houbraken & Samson 2008, Aspergillus sp. JV-2007c, CBS 121601
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.