STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASPCAL08506Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (511 aa)    
Predicted Functional Partners:
ASPCAL03816
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
 
 
 0.989
ASPCAL08437
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.964
ASPCAL13119
Putative Phosphomevalonate kinase.
   
 
 0.954
ASPCAL11174
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.906
ASPCAL03522
Putative Cystathionine beta-lyase.
 
      0.899
ASPCAL11787
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.885
ASPCAL11391
Putative Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.834
ASPCAL00840
Putative Inositol oxygenase.
   
 
 0.820
ASPCAL11431
Putative Cystathionine gamma-lyase.
 
      0.788
ASPCAL12774
Uncharacterized protein.
  
 0.764
Your Current Organism:
Aspergillus calidoustus
NCBI taxonomy Id: 454130
Other names: A. calidoustus, Aspergillus calidoustus Varga, Houbraken & Samson 2008, Aspergillus sp. JV-2007c, CBS 121601
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